||Molecular Detection of Carbapenemase
||CARBAR, KPC Detection, CRE
||PCR; Cepheid Xpert Carba-R
||NPHL Special Microbiology Requisition and Special Microbiology Supplemental Form Required. Test performed Monday-Friday.
||Carbapenem Resistant Organism Guidelines:
- Submission of all isolates of Enterobacteriaceae that are non-susceptible (intermediate or resistant) to any of the carbapenems
- Exceptions are Enterobacter cloacae and E.aerogenes: only submit isolates that are non-susceptible to Carbapenems other than ertapenem
- Submission of all non-mucoid isolates of Pseudomonas aeruginosa that are non-susceptible to carbapenems other than ertapenem from non-cystic fibrosis patients
| Collection Device:
||Isolate area on media slant or plate, sealed with parafilm or tape.
Specimen Labeling: Test subject to CLIA regulations and required 2 patient identifiers on specimen container and requisition forms
||One agar or slant
||Prior to shipment: Ambient air
Shipping instructions, including specimen handling requirements during transport: Package and ship ambient as Category B, Biological Substance, UN3373 using shipping material provided by NPHL. See instructions and shipping address: http://nphl.org . If courier not available, contact Client Services (866) 290-1406 to arrange pickup.
||Organisms that do not meet the requirements outlined on the supplemental requisition or submitted without the supplemental requisition
| Specimen Stability:
||Stable at ambient temperatures
| Reference Interval:
| Reportable Disease:
||All carbapenemase-resistant Enterobacteriaceae will be reported immediately to local or state health department.
||Testing results are to be used for epidemiological and infection control purposes only.
The confirmation of a carbapenemase-resistant Enterobacteriaceae need to be reported immediately to the in-house infection control official.